Op 1 maart 2024 organiseert VENI haar jaarlijkse lezingenavond. Voor het eerst organiseren wij die volledig in samenwerking met de Vereniging van Scheikundige Ingenieurs Eindhoven (VSI/e) rondom één centraal thema: nucleaire technologie.

Op deze avond zullen lezingen worden gegeven over de nieuwbouw van Nederlandse kernreactor PALLAS, over onderzoek naar en productie van medische isotopen en over onderzoek naar de eindbergingsstrategieën. In al deze onderzoekslijnen is een mooie mix van natuur- en scheikunde te vinden, dus we zijn er van overtuigd dat er weer een mooie avond van gemaakt zal worden.

Locatie

Gebouw Helix, TU/e, Eindhoven

Programma

18h00 Inloop
18h15 Eten

19h00 Welkom door VSI/e & VENI
19h10 Creating hope for cancer patients : making 225Ac accessible door Sven van den Berghe, PANTERA
19h50 PALLAS: Nucleair New Build in the Netherlands door Stijn Franssen–Rijsingen, NRG
20h30 Pauze
20h40 Geological disposal of radioactive waste door Erika Neeft, COVRA
21h20 Afsluiting door VSI/e & VENI

21h30 Borrel
22h30 Einde

Abstracten

Creating hope for cancer patients: making 225Ac accessible | Sven van den Berghe (Pantera)

Our core belief is that these powerful medical tools deserve a central role in oncology for their potential to treat cancers effectively while preserving patient’s quality of life. Our focus is on the radiotheranostics field, which facilitates patient-tailored optimization of treatment by tracking the distribution of therapeutic agents in the body. This cutting-edge approach minimizes patient side-effects while enhancing treatment efficacy.

Our vision is to make such personalized nuclear medicine treatments a reality, making them widely available and affordable. To realize this vision, we are establishing a state-of-the-art production facility for actinium-225 (225Ac) in Mol, Belgium. Our unique production process, employing the photonuclear or ‘gamma’ route, transforms radium-226 (226Ra) into 225Ra, which in turn decays into 225Ac. This high-purity 225Ac is then supplied as an Active Product Ingredient (API) to the global pharmaceutical market.

In addition to ensuring quality, we prioritize sustainability. The radium in our process is recycled and reused, emphasizing our commitment to environmentally friendly practices. At PanTera, we are not only supporting the development of the next generation of cancer treatments but also fostering a future where personalized nuclear medicine is the norm.

PALLAS: Nuclear New Build in the Netherlands | Stijn Franssen–Rijsingen (PALLAS/NRG)

For the first time since 1973 a new reactor is being built in the Netherlands. The PALLAS reactor in Petten will replace the High Flux Reactor (HFR) that has been operational for the past fifty years. The HFR was originally designed as a research reactor, and only later modified to allow for the production of larger quantities of (medical) isotopes for which Petten is known today. The PALLAS reactor has been designed to meet the growing demand for medical isotopes in the market. This presentation go into the design of PALLAS, the current state of its construction and the envisaged usage.

Geological disposal of radioactive waste | Erika Neeft (COVRA)

Some types of radioactive waste remain hazardous for thousands of years. Disposal of the waste in stable geological formations is the solution for this long-lived waste according to the current state of technology and science. This is done by placing packages with radioactive waste in an underground facility, hundreds of metres below the land surface. After closure of a facility, isolation of the waste and containment of the radionuclides are achieved by a disposal system consisting of engineered barriers, the geological formation and surrounding rock formations.

This geological disposal of radioactive waste has been studied in the Netherlands for more than four decades. Suitable geological formations in the Netherlands are million year old poorly indurated clay layers and rock salt domes, pillows and beds. Clays have a very small water permeability, reducing conditions which limits the solubility of many metals and redox sensitive elements and solid phases to which radionuclides stick if these radionuclides would be released from the engineered barriers. All remaining million year old existing rock salt formations are surrounded by insoluble materials such as clay and anhydrite. This current preservation of rock salt provides the evidence that radionuclides from the waste can also sufficiently be contained in rock salt formations.

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